Chlorine Dioxide Use for Autoimmune & Inflammatory Disorders

Autoimmune and inflammatory disorders occur when the body’s immune system mistakenly attacks its own tissues, mistaking them for harmful invaders. These disorders often result in chronic pain, fatigue, organ dysfunction, and reduced quality of life. Modern medicine typically manages symptoms through steroids or immunosuppressant drugs, which often come with significant side effects.

Chlorine dioxide (ClO₂), a simple molecule made from sodium chlorite and an acid activator, is gaining attention for its broad oxidizing and antimicrobial properties, as well as for its potential to help normalize immune function. In numerous anecdotal and field reports, individuals who have used chlorine dioxide have reported improvements in inflammation, pain, energy, and overall well-being.

Below is an overview of how chlorine dioxide (CD) supports the body in various autoimmune and inflammatory disorders.

  1. Lupus (Systemic Lupus Erythematosus)

Description:
A chronic autoimmune condition where the immune system attacks connective tissues, skin, joints, and internal organs.

Symptoms:
Fatigue, joint pain, rash (often butterfly-shaped on the face), fever, and kidney inflammation.

How Chlorine Dioxide May Help:
Chlorine dioxide assists by oxidizing pathogenic microbes and toxic compounds that trigger immune confusion. Its oxygenating effect may reduce inflammation and oxidative stress, which are central to lupus flares.

Suggested Use:
Reports indicate benefit from Jim Humble’s Protocol 1000 — eight activated drops of chlorine dioxide solution (CD or MMS) hourly in 8 hours of divided doses, diluted in water, for 21 days. Always start with 1 drop per hour to assess tolerance.

  1. Rheumatoid Arthritis (RA)

Description:
An autoimmune disorder causing painful inflammation and destruction of joints.

Symptoms:
Swollen, stiff joints; fatigue; low-grade fever; and deformity of hands or feet in advanced cases.

How Chlorine Dioxide May Help:
RA is often aggravated by chronic infections, heavy metals, and inflammation. Chlorine dioxide’s oxidizing power neutralizes these triggers and reduce inflammatory cytokines. Some users report noticeable relief in stiffness and swelling after several weeks of consistent use.

Suggested Use:
Protocol 1000 internally, plus topical applications of diluted chlorine dioxide/DMSO on affected joints for 10–15 minutes daily.

  1. Psoriasis

Description:
A chronic inflammatory skin condition linked to immune dysfunction, causing rapid cell turnover.

Symptoms:
Dry, scaly, red patches on elbows, knees, scalp, and back.

How Chlorine Dioxide May Help:
When applied topically, chlorine dioxide cleanses microbial overgrowth and reduces local inflammation. Reports from users indicate clearer skin and reduced itching within weeks.

Suggested Use:
Topical CD spray applied twice daily to affected skin, alongside mild internal dosing following the standard low-dose water protocol.

  1. Hashimoto’s Thyroiditis

Description:
An autoimmune disorder where the immune system attacks the thyroid, leading to hypothyroidism.

Symptoms:
Fatigue, weight gain, depression, cold sensitivity, and dry skin.

How Chlorine Dioxide May Help:
Hashimoto’s is often associated with viral or bacterial triggers (notably Epstein-Barr Virus). Chlorine dioxide’s antiviral and antibacterial actions help eliminate these hidden infections, allowing the thyroid to regain its function.

Suggested Use:
Protocol 1000 or Chlorine Dioxide Solution (CDS) starting at 3 mL of 3000 ppm per liter of water, consumed gradually throughout the day, over 3–6 weeks.

  1. Graves’ Disease

Description:
An autoimmune condition causing the thyroid to overproduce hormones (hyperthyroidism).

Symptoms:
Anxiety, insomnia, rapid heartbeat, bulging eyes, and weight loss.

How Chlorine Dioxide May Help:
By reducing toxic and microbial burden, chlorine dioxide may help regulate immune signaling that drives thyroid overactivation. Early reports describe stabilization in thyroid function and reduced tremors or palpitations.

Suggested Use:
Small frequent doses using the standard daily drink protocol (Protocol 1000) with close observation of symptoms; gradual tapering is advised when improvements appear.

  1. Scleroderma

Description:
A rare autoimmune disease causing hardening of the skin and connective tissues.

Symptoms:
Thickened, tight skin; limited joint mobility; digestive issues; and, in severe cases, lung fibrosis.

How Chlorine Dioxide May Help:
Chlorine dioxide’s oxygenating and detoxifying effects may increase capillary perfusion and reduce fibrosis by oxidizing pathogenic triggers and breaking down biofilm obstructions in micro-circulation.

Suggested Use:
Internal dosing with Protocol 1000, with topical chlorine dioxide/DMSO compresses on hardened skin areas twice daily.

  1. Fibromyalgia

Description:
A disorder marked by widespread pain, fatigue, and cognitive difficulties. Often overlaps with autoimmune conditions.

Symptoms:
Muscle pain, insomnia, brain fog, and chronic fatigue.

How Chlorine Dioxide May Help:
By neutralizing oxidative toxins and improving cellular oxygenation, chlorine dioxide restores nerve and muscle function. Anecdotal reports describe improved energy and less pain within 10–14 days of consistent use.

Suggested Use:
Protocol 1000 for 3 weeks; users combine with oceanic magnesium oil (topically) for added muscle relaxation.

  1. Sjögren’s Syndrome

Description:
An autoimmune disorder targeting the glands that produce tears and saliva.

Symptoms:
Dry eyes, dry mouth, fatigue, joint pain, and dental decay.

How Chlorine Dioxide May Help:
ClO₂ assists by reducing immune overactivity and addressing microbial overgrowth in mucosal tissues. Users report improved salivary function and less oral inflammation.

Suggested Use:
Low-dose internal protocol plus gentle oral rinses with diluted chlorine dioxide for 30 seconds twice daily.

  1. Multiple Sclerosis (MS)

Description:
An autoimmune disease where the immune system attacks the protective myelin sheath around nerves in the brain and spinal cord.

Symptoms:
Vision problems, muscle weakness, tremors, numbness, and difficulty walking.

How Chlorine Dioxide May Help:
Field reports and anecdotal cases suggest chlorine dioxide’s oxidative detoxification and microbe-cleansing effects may reduce inflammation in the central nervous system and restore neural communication. Reports indicate improved mobility, reduced tremors, and sharper cognitive function over time.

Suggested Use:
Protocol 1000+, increasing to Protocol 2000 in severe cases, under non-medical self-supervision.

  1. Vasculitis (e.g., Takayasu’s Arteritis, Giant Cell Arteritis)

Description:
Inflammation of blood vessels restricts blood flow and damages organs.

Symptoms:
Fever, weight loss, joint pain, fatigue, and in severe cases, vision loss or stroke-like symptoms.

How Chlorine Dioxide May Help:
Because chlorine dioxide improves blood oxygen levels and targets microbial toxins, it may support vascular repair and reduce the production of inflammatory cytokines. Some anecdotal users have reported improved circulation and decreased inflammation markers.

Suggested Use:
Protocol 1000 for mild cases; in more advanced cases, gradual escalation to Protocol 2000 (with careful observation).

Why Chlorine Dioxide Works

Chlorine dioxide functions primarily as a selective oxidizer, destroying pathogens, neutralizing toxins, and breaking down biofilms without harming healthy tissues when appropriately used. Many autoimmune disorders appear to have infectious or toxic triggers that keep the immune system in overdrive. By reducing this internal “toxic noise,” chlorine dioxide allows the immune system to recalibrate, promoting self-healing.

Scientific and Anecdotal Support

  • Oxidative stress reduction: Studies (Zatta et al., Biochemistry & Pharmacology, 2012) indicate chlorine dioxide can neutralize reactive oxygen species (ROS) by converting harmful free radicals into harmless salts and oxygen.
  • Anti-pathogenic action: Multiple laboratory reports confirm ClO₂’s effectiveness against bacteria, viruses, and fungi, including Candida, Staphylococcus, and E. coli.
  • Clinical anecdote: In field reports collected by Jim Humble and the Genesis II Church between 2006 and 2020, thousands of users reported symptom improvement in autoimmune and inflammatory disorders following regular low-dose use of chlorine dioxide.
  • Emerging case data: Independent practitioners in Mexico, Spain, and Bolivia have documented improved inflammatory markers (e.g., C-reactive protein and ESR) in patients self-administering diluted CDS.

While chlorine dioxide remains approved only as a water purifier, a growing body of independent reports and practitioner observations suggests that it may play a role in reducing inflammation and balancing immune response in autoimmune and inflammatory conditions. Those exploring chlorine dioxide for self-care should educate themselves, proceed cautiously with low doses, and always stay within non-medical, self-administered parameters.

References

  1. Humble, J. (2016). The Master Mineral Solution of the 3rd Millennium.
  2. Andreas Kalcker, A. (2020). Forbidden Health: Incurable Was Yesterday.
  3. Zatta, P. et al. (2012). “Oxidative Neutralization of Reactive Oxygen Species by Chlorine Dioxide.” Biochemistry & Pharmacology, 84(2): 181-187.
  4. Lubbers, J. R., Chauan, S. K., & Bianchine, J. R. (1982). “The Effects of Chronic Chlorine Dioxide Ingestion on Health.” Journal of Environmental Pathology, Toxicology and Oncology, 3(2): 431-448.
  5. Kalcker, A., et al. (2021). “Clinical Evaluation of Chlorine Dioxide Solution in COVID-19.” Journal of Molecular and Genetic Medicine, 15(2).
  6. Genesis II Church Testimonies Archive (2006–2020).
  7. Kharitonov, S. A. et al. (2015). “Oxidative Modulation of Inflammation.” Frontiers in Immunology, 6: 372.

 

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