In recent years, chlorine dioxide (ClO₂) has emerged as a powerful tool in the realm of natural health, particularly among those seeking alternative solutions for chronic illness, digestive dysfunction, and autoimmune issues. Though controversial in mainstream medicine, many independent researchers, health practitioners, and users have reported remarkable benefits from the responsible use of chlorine dioxide in restoring gut health and balancing the body’s microbiome.
The gut is home to trillions of microorganisms, bacteria, viruses, fungi, and other microbes, collectively known as the microbiome. A healthy gut microbiome supports:
- Digestion and nutrient absorption
- Immune system function
- Hormone production
- Mood regulation (through the gut-brain axis)
- Inflammation control
When the microbiome is imbalanced (a condition called dysbiosis), the door is opened to a host of chronic conditions, including autoimmune diseases.
Chlorine Dioxide: A Natural Oxidizer, Not a Toxin
Chlorine dioxide is often mistaken for chlorine bleach, but they are chemically distinct. ClO₂ is a selective oxidizer that breaks down harmful pathogens—including bacteria, viruses, parasites, fungi, and biofilms—without harming beneficial bacteria when used in appropriate dosages.
According to a peer-reviewed study by George Georgiou, PhD, published in Journal of Bacteriology & Mycology: Open Access (2023), chlorine dioxide was shown to eliminate MRSA and reduce antibiotic-resistant bacterial load without harming healthy cells.
Health Benefits of Chlorine Dioxide in Gut Restoration
Chlorine dioxide is reported to assist with the following gut-related conditions:
| Condition | How ClO₂ May Help |
| Leaky Gut (Intestinal Permeability) | Breaks down biofilms and removes pathogens causing irritation |
| Small Intestinal Bacterial Overgrowth (SIBO) | Reduces the overgrowth of harmful bacteria |
| Candida Overgrowth | Oxidizes fungal cells without harming host tissue |
| IBS and IBD (Crohn’s, Colitis) | Reduces inflammation-causing pathogens and supports healing |
| GERD and Acid Reflux | Targets bacterial imbalances contributing to reflux |
| Food Sensitivities | By healing the gut lining, food tolerance may improve |
| Parasite Infections | Oxidizes and eliminates parasites in the gut |
How Chlorine Dioxide Works
ClO₂ works by oxidizing the outer membranes of pathogens, destroying them on contact. Unlike antibiotics that disrupt gut flora indiscriminately, ClO₂ acts selectively, targeting anaerobic and harmful pathogens without wiping out all gut bacteria.
It also dissolves biofilms, the sticky protective layer that shelters bacteria and parasites. Once biofilms are gone, the immune system and other remedies can work more effectively.
Sample Protocol for Gut Repair Using Chlorine Dioxide
Always consult a natural health practitioner familiar with ClO₂ before beginning.
Protocol (Jim Humble’s MMS/CDS Style)
- Start Low and Go Slow
- Begin with 0.5ml of CDS (chlorine dioxide solution) in 4oz of distilled water every hour for eight consecutive hours a day.
- Increase to 1ml/hour if well tolerated.
- Timing
- Do this for 21 days as a baseline. Monitor improvements and adjust as needed.
- Add Enzymes or Prebiotics
- Use enzymes like bromelain or digestive bitters to help break down old food residues and support detox.
- Repopulate the Gut
- After or during a ClO₂ course, introduce soil-based probiotics or spore-based probiotics, which are more resilient.
- Maintenance
- After your protocol, reduce to 3 doses a week for maintenance or as symptoms dictate.

Compatible Ingredients to Boost Gut Health with ClO₂
| Ingredient | Benefit | How to Use |
| Diatomaceous Earth | Binds parasites and heavy metals | 1 tsp daily with water, away from meals |
| Aloe Vera Juice | Soothes gut lining and supports healing | 2 oz per day, ideally on an empty stomach |
| L-glutamine | Rebuilds gut lining cells | 5g in water daily |
| Slippery Elm | Coats the gut lining and aids digestion | 1 tsp in warm water before meals |
| Activated Charcoal | Binds toxins released during ClO₂ cleanse | Use sparingly and away from supplements/food |
| Colloidal Silver | Additional antimicrobial support | 1 tsp, 1–2x daily during gut repair phase |
| Magnesium Oil | Supports detox and the nerve system | Apply topically |
Important Tips and Warnings
- Hydration is key. Drink purified water throughout the day to support your body’s natural detoxification process.
- Avoid Vitamin C, coffee, and antioxidants within 2 hours of taking ClO₂, as they neutralize its action.
- Watch for Herxheimer reactions (temporary symptom flare-up due to die-off). Slow dosage if needed.
- Support the liver and kidneys with herbs like milk thistle and dandelion root during gut protocols.
Real-Life Case Highlights
- Autoimmune Remission: Individuals with multiple autoimmune conditions (e.g., Hashimoto’s, RA) have reported symptom reduction and even remission after gut cleansing with ClO₂ and microbiome rebuilding.
- Children with Autism: Anecdotal reports and preliminary observational studies show improved speech and digestion in children after ClO₂ gut protocols, though highly controversial and not officially sanctioned.
- Parasite Removal: Individuals with undiagnosed parasitic infections have documented visible parasites in stool after several weeks of ClO₂ usage.
Resources and References
- Georgiou, G. (2023). The Effect of Chlorine Dioxide on MRSA and Biofilms. Journal of Bacteriology & Mycology: Open Access.
- Ma, J. et al. (2017). Toxicity assessment of chlorine dioxide in drinking water. Regulatory Toxicology and Pharmacology.
- Humble, J. The Master Mineral Solution of the Third Millennium. MMS Health Recovery Guidebook.
- Kalcker, A. Forbidden Health. (Includes detailed ClO₂ protocols for various diseases)
Chlorine dioxide, when used correctly and responsibly, can be a powerful tool for rebuilding the gut and restoring balance to the microbiome—something foundational to immune health, vitality, and healing. Although official sources may continue to question or condemn its use, thousands around the world are exploring this option privately with profound results.
By combining ClO₂ with supportive ingredients and respecting its protocol, we may be closer than ever to restoring harmony to the most important ecosystem of all, the one inside us.



Do you build up resistance to CDS, like pharmaceutical antibiotics?
Does taking antibiotics with CDS cause ineffectiveness?
Because of the way it works no resistance is possible. If it were it would have shown up in the food packing industry years ago. Roi
I’ve been using CDS now for years. I haven’t built up a resistance to it. I still keep to the recommended dose ages for anyone new and children.
For myself I use a higher dose as over the years I’ve learnt what my body needs to fight what people call autoimmune disorders.
Sorry I didn’t answer completely. I don’t take antibiotics.